Luminescent Ruthenium(II) Polypyridyl Functionalized Gold Nanoparticles; Their DNA Binding Abilities and Application As Cellular Imaging Agents.

Authors :: Elmes, Robert B. P.
Orange, Kim N.
Cloonan, Suzanne M.
Williams, D. Clive
Gunnlaugsson, Thorfinnur
Source :: Journal of the American Chemical Society. 10/12/2011, Vol. 133 Issue 40, p15862-15865. 4p.
Publication Year :: 2011
Abstract: The synthesis and photophysical and biological investigation of Ru(II)-polypyridyl stabilized water-soluble, luminescent gold nanoparticles (AuNPs) are described. These structures bind to DNA and undergo rapid cellular uptake, being localized within the cell cytoplasm and nucleus within 4 h. [ABSTRACT FROM AUTHOR]

Subjects :: *NANOSTRUCTURES
*PHOTONICS
*RUTHENIUM
*NANOPARTICLES
*CATALYSIS
*GOLD metallurgy
*CYTOPLASM

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