Transcriptional Repressors: Shutting Off Gene Expression at the Source Affects Developmental Dynamics

Authors :: Arnosti, David N.
Source :: Current Biology. Oct2011, Vol. 21 Issue 20, pR859-R860. 0p.
Publication Year :: 2011
Abstract: Summary: Developmental networks feature genes interlinked by transcriptional activation and repression. A new study indicates that repressors can ‘shut the door’ to newly initiating polymerases, allowing longer target genes to produce latent transcripts after shorter genes have been effectively silenced. [ABSTRACT FROM AUTHOR]

Subjects :: *TRANSCRIPTION factors
*GENE expression
*DEVELOPMENTAL biology
*GENETIC repressors
*DNA polymerases
*GENE silencing
*GENE targeting

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