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Efficient and stereoselective syntheses of DAB-1 and d-fagomine via chiral 1,3-oxazine

Authors :
Kim, Ji-Yeon
Mu, Yu
Jin, Xiangdan
Park, Seok-Hwi
Pham, Van-Thoai
Song, Dong-Keun
Lee, Kee-Young
Ham, Won-Hun
Source :
Tetrahedron. Dec2011, Vol. 67 Issue 48, p9426-9432. 7p.
Publication Year :
2011

Abstract

Abstract: The concise, stereocontrolled syntheses of DAB-1 and d-fagomine were achieved utilizing chiral oxazine. The key features in these strategies are the stereoselective intramolecular oxazine formation catalyzed by palladium(0), and pyrrolidine and piperidine formation by catalytic hydrogenation of oxazine. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
00404020
Volume :
67
Issue :
48
Database :
Academic Search Index
Journal :
Tetrahedron
Publication Type :
Academic Journal
Accession number :
67130105
Full Text :
https://doi.org/10.1016/j.tet.2011.09.084