Back to Search
Start Over
Chemical Synthesis of Integral Membrane Proteins: Methods and Applications.
- Source :
-
Israel Journal of Chemistry . Nov2011, Vol. 51 Issue 8/9, p940-952. 13p. - Publication Year :
- 2011
-
Abstract
- The development of efficient chemical methods for total synthesis or semisynthesis of integral membrane proteins is an important challenge at the interface between chemistry and biology. This review outlines the recent advances in the synthesis of integral membrane proteins, with particular focus on the methods for difficult peptide synthesis, purification, and enhancement of peptide solubility under the ligation conditions. The applications of these methods to the synthesis of integral membrane proteins with one or multiple transmembrane domains are also described. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00212148
- Volume :
- 51
- Issue :
- 8/9
- Database :
- Academic Search Index
- Journal :
- Israel Journal of Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 67226153
- Full Text :
- https://doi.org/10.1002/ijch.201100076