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Vertebral fracture and cause-specific mortality: a prospective population study of 3,210 men and 3,730 women with 30 years of follow-up.
- Source :
-
European Spine Journal . Dec2011, Vol. 20 Issue 12, p2181-2186. 6p. 2 Charts. - Publication Year :
- 2011
-
Abstract
- Introduction: Vertebral fractures predict mortality, but little is known about their associations with the causes of death. We studied vertebral fractures for prediction of cause-specific mortality. Material and methods: A nationally representative sample of 3,210 men and 3,730 women participated Mini-Finland health survey in 1978-1980. Vertebral fractures at the Th1-Th12 levels were identified from chest radiographs at baseline. Cox's proportional hazard model was used to estimate the strength of association between vertebral fracture and mortality. Results: The relative risk (95% confidence interval) of death from natural causes was 1.49 (0.89-2.48) in men and 0.89 (0.60-1.31) in women with vertebral fractures (adjusted for age, body mass index, serum 25-hydroxyvitamin D, educational level, smoking, alcohol intake, physical activity and self-rated general health). Among women the adjusted relative risk of an injury death was 8.51 (3.48-20.77), whereas none of the men with vertebral fracture died due to an injury. Conclusion: The patterns of mortality predicted by fracture in the thoracic spine differ between men and women. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09406719
- Volume :
- 20
- Issue :
- 12
- Database :
- Academic Search Index
- Journal :
- European Spine Journal
- Publication Type :
- Academic Journal
- Accession number :
- 67647220
- Full Text :
- https://doi.org/10.1007/s00586-011-1852-0