Decreased insulin action in skeletal muscle from patients with McArdle's disease.

Authors :: Nielsen, Jakob N.
Vissing, John
Wojtaszewski, Jorgen F.P.
Haller, Ronald G.
Begum, Najma
Richter, Erik A.
Source :: American Journal of Physiology: Endocrinology & Metabolism. Jun2002, Vol. 45 Issue 6, pE1267. 9p. 1 Black and White Photograph, 5 Charts, 5 Graphs.
Publication Year :: 2002
Abstract: Presents a study that examined the effect of glycogen on insulin action in the skeletal muscles of patients with McArdle's disease, a kind of glycogen storage disease. Impact of glycogen on insulin-stimulated glucose utilization; Effect of glycogen on glycogen synthase activity; Examination of the activity of insulin-signaling intermediaries.

Subjects :: *GLYCOGEN
*GLYCOGEN storage disease
*PHYSIOLOGY
MECHANISM of action for insulin

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