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Longitudinal evaluation of cartilage after osteochondral autogenous transfer with delayed gadolinium-enhanced MRI of the cartilage (dGEMRIC).
- Source :
-
Journal of Orthopaedic Research . Feb2012, Vol. 30 Issue 2, p221-225. 5p. - Publication Year :
- 2012
-
Abstract
- The aim was to use repeat delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) to estimate glycosaminoglycan (GAG) content in reparative cartilage after osteochondral autogenous transfer (OAT). The study group comprised 7 knees of 7 patients that were examined three times by dGEMRIC, at 3, 6, and 12 months using a 1.5 Tesla MRI system in both OAT operated and nonoperated condyles at 90 min after the injection. The gadolinium diethylene triamine pentaacetic acid (Gd-DTPA)2− containing contrast medium (0.2 mmols/kg) was injected intravenously. The mean T1 values of the plug cartilage at 3, 6, and 12 months after OAT was 230 ± 40, 213 ± 31, and 230 ± 23 ms (mean ± SD), respectively. There were differences between the plug and control cartilage at 3 ( p < 0.01) and 12 ( p < 0.05) months after OAT, but not at 6 months ( p = 0.089). No T1 changes were detected between the plug cartilage at the different time points after OAT. The fact that the GAG content of the OAT plugs were maintained for 12-month study period suggest that no major deterioration of load-bearing properties occurs in the cartilage after the OAT. © 2011 Orthopaedic Research Society Published by Wiley Periodicals, Inc. J Orthop Res 30:221-225, 2012 [ABSTRACT FROM AUTHOR]
- Subjects :
- *GADOLINIUM
*MAGNETIC resonance imaging
*CARTILAGE
*GLYCOSAMINOGLYCANS
*ORTHOPEDICS
Subjects
Details
- Language :
- English
- ISSN :
- 07360266
- Volume :
- 30
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Journal of Orthopaedic Research
- Publication Type :
- Academic Journal
- Accession number :
- 69734527
- Full Text :
- https://doi.org/10.1002/jor.21514