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Risk of nosocomial infection with human T-cell lymphotropic virus type III/lymphadenopathy-associated virus in a large cohort of intensively exposed health care workers.
- Source :
-
Annals of Internal Medicine . May86, Vol. 104 Issue 5, p644-647. 4p. 2 Charts. - Publication Year :
- 1986
-
Abstract
- To assess the risk of nosocomial transmission of human T-cell lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV), we prospectively evaluated a cohort of 531 health care workers. One hundred fifty of these employees reported percutaneous or mucous membrane exposures to blood or body fluids from a patient with the acquired immunodeficiency syndrome (AIDS) during the treatment of 238 such patients since 1981. None of these 150 employees had serologic evidence of HTLV-III/LAV infection on follow-up from 6 to 46 months after exposure. Of the 150, 46 were studied immunologically and 29 had lymphocytes cultured for HTLV-III/LAV. Results of all studies were normal. Of the 531 employees, 3 (0.56%) had serologic evidence of HTLV-III/LAV infection. All were seropositive at the time of study entry; none reported adverse nosocomial exposures. All acknowledged membership in one or more established risk groups for AIDS. This study provides strong evidence that the risk of nosocomial transmission of HTLV-III/LAV is extremely low. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HIV
*MEDICAL personnel
*INFECTIOUS disease transmission
*DISEASES
Subjects
Details
- Language :
- English
- ISSN :
- 00034819
- Volume :
- 104
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Annals of Internal Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 7007646
- Full Text :
- https://doi.org/10.7326/0003-4819-104-5-644