TREAT: a bioinformatics tool for variant annotations and visualizations in targeted and exome sequencing data.

Summary: TREAT (Targeted RE-sequencing Annotation Tool) is a tool for facile navigation and mining of the variants from both targeted resequencing and whole exome sequencing. It provides a rich integration of publicly available as well as in-house developed annotations and visualizations for variants, variant-hosting genes and host-gene pathways.Availability and implementation: TREAT is freely available to non-commercial users as either a stand-alone annotation and visualization tool, or as a comprehensive workflow integrating sequencing alignment and variant calling. The executables, instructions and the Amazon Cloud Images of TREAT can be downloaded at the website: http://ndc.mayo.edu/mayo/research/biostat/stand-alone-packages.cfmContact: Hossain.Asif@mayo.edu; Kocher.JeanPierre@mayo.eduSupplementary information: Supplementary data are provided at Bioinformatics online. [ABSTRACT FROM PUBLISHER]