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Full Surface Embeddingof Gold Clusters on Silicon Nanowires for Efficient Capture and PhotothermalTherapy of Circulating Tumor Cells.
- Source :
-
Nano Letters . Mar2012, Vol. 12 Issue 3, p1638-1642. 5p. - Publication Year :
- 2012
-
Abstract
- We report on rapid thermal chemical vapor depositiongrowth of silicon nanowires (Si NWs) that contain a high density ofgold nanoclusters (Au NCs) with a uniform coverage over the entirelength of the nanowire sidewalls. The Au NC-coated Si NWs with anantibody-coated surface obtain the unique capability to capture breastcancer cells at twice the highest efficiency currently achievable(â¼88% at 40 min cell incubation time) from a nanostructuredsubstrate. We also found that irradiation of breast cancer cells capturedon Au NC-coated Si NWs with a near-infrared light resulted in a highmortality rate of these cancer cells, raising a fine prospect forsimultaneous capture and plasmonic photothermal therapy for circulatingtumor cells. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15306984
- Volume :
- 12
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Nano Letters
- Publication Type :
- Academic Journal
- Accession number :
- 73768950
- Full Text :
- https://doi.org/10.1021/nl2045759