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Eco-friendly synthesis of α-aminonitriles from ketones in PEG-400 medium using potassium Hexacyanoferrate(II) as cyanide source
- Source :
-
Journal of Organometallic Chemistry . May2012, Vol. 705, p70-74. 5p. - Publication Year :
- 2012
-
Abstract
- Abstract: An efficient method for the synthesis of α-aminonitriles via one-pot three-component condensation of ketones, amines and potassium hexacyanoferrate(II) using benzoyl chloride as a promoter and PEG-400 as a reaction medium was described. This protocol has the features of use of eco-friendly cyanide source, green reaction medium, high yield, and simple work-up procedure. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 0022328X
- Volume :
- 705
- Database :
- Academic Search Index
- Journal :
- Journal of Organometallic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 73777347
- Full Text :
- https://doi.org/10.1016/j.jorganchem.2012.02.005