Endoscopic Transgastric vs Surgical Necrosectomy for Infected Necrotizing Pancreatitis: A Randomized Trial.

Authors :: Bakker, Olaf J.
van Santvoort, Hjalmar C.
van Brunschot, Sandra
Geskus, Ronald B.
Besselink, Marc G.
Bollen, Thomas L.
van Eijck, Casper H.
Fockens, Paul
Hazebroek, Eric J.
Nijmeijer, Rian M.
Poley, Jan-Werner
van Ramshorst, Bert
Vleggaar, Frank P.
Boermeester, Maria A.
Gooszen, Hein G.
Weusten, Bas L.
Timmer, Robin
Source :: JAMA: Journal of the American Medical Association. 3/14/2012, Vol. 307 Issue 10, p1053-1061. 9p. 2 Diagrams, 2 Charts, 1 Graph.
Publication Year :: 2012
Abstract: The article discusses a randomized study of the proinflammatory response (PR) and clinical outcome of endoscopic transgastric (ET) and surgical necrosectomy (SN) for patients with infected necrotizing pancreatitis (INP). The researchers randomized 22 patients with signs of INP and had an indication for intervention in 3 academic hospitals and one regional teaching hospital in the Netherlands between August 20, 2008 and March 3, 2010. They found that ET lowered the PR and the composite clinical end point compared with SN. INSET: Box. Definitions of Clinical End Points.

Subjects :: *NECROTIZING pancreatitis
*CLINICAL trials
*STOMACH surgery
*ENDOSCOPIC surgery
*TEACHING hospitals

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