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Synthesis of 5-Fluoro N-Acetylglucosamine Glycosides and Pyrophosphates via Epoxide Fluoridolysis: Versatile Reagents for the Study of Glycoconjugate Biohchemistry.

Authors :
Hartman, Matthew C.T.
Coward, James K.
Source :
Journal of the American Chemical Society. 8/28/2002, Vol. 124 Issue 34, p10036. 18p. 16 Diagrams, 3 Charts, 1 Graph.
Publication Year :
2002

Abstract

Reports on the development of a method for the introduction of 5-fluoro group for easy access to a wide variety of 5-fluoro glycosides and glycosyl phosphates. Fluoridolysis of C-5, 6 epoxides; Synthesis of two fluorinated carbohydrates.

Details

Language :
English
ISSN :
00027863
Volume :
124
Issue :
34
Database :
Academic Search Index
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
7414161
Full Text :
https://doi.org/10.1021/ja0127234