The Williams syndrome chromosome 7q11.23 hemideletion confers hypersocial, anxious personality coupled with altered insula structure and function.

Authors :: Jabbi, Mbemba
Kippenhan, J. Shane
Kohn, Philip
Marenco, Stefano
Mervis, Carolyn B.
Morris, Colleen A.
Meyer-Lindenberg, Andreas
Berman, Karen Faith
Source :: Proceedings of the National Academy of Sciences of the United States of America. 4/3/2012, Vol. 109 Issue 14, p5164-5165. 5p.
Publication Year :: 2012
Abstract: The article presents a study of the association among genes, personality traits and neural alterations in Williams syndrome (WS). The study focused on insula structure and function to examine the brain interface between behavioral and genetic features of WS. Results suggest the role of insula in brain circuitry and human social emotional processes.

Subjects :: *WILLIAMS syndrome
*SOCIETAL reaction
*PERSONALITY
*NEURAL circuitry
*SOCIAL processes
*GENETICS

Language :: English
ISSN :: 00278424
Volume :: 109
Issue :: 14
Database :: Academic Search Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 74200883
Full Text :: https://doi.org/10.1073/pnas.1114774109

Full Text Access

Tools