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Antiapoptotic Cdc42 Mutants Are Potent Activators of Cellular Transformation.

Authors :
Tu, Shine S.
Wen Jin Wu
Wannian Yang
Nolbant, Peri
Hahn, Klaus
Cerione, Richard A.
Source :
Biochemistry. 10/15/2002, Vol. 41 Issue 41, p12350. 9p. 2 Color Photographs, 2 Black and White Photographs, 9 Graphs.
Publication Year :
2002

Abstract

Describes the role of antiapoptotic Cdc42 mutants on cellular transformation. Conservation of aspartic residues; Induction of cellular transformation; Stimulation of GDP-GTP exchange reaction.

Details

Language :
English
ISSN :
00062960
Volume :
41
Issue :
41
Database :
Academic Search Index
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
7586209
Full Text :
https://doi.org/10.1021/bi026167h