Síndrome de Wells (celulitis eosinofílica) asociado con infección por Helicobacter pylori.

Wells' syndrome is a rare eosinophilic dermatitis first described 40 years ago, with a wide clinical spectrum and varied histology according to the stage of the cutaneous lesions, associated with numerous endogenous and exogenous factors, including infectious and gastrointestinal diseases. We present the case of a woman with a 10-day history of edematous, itching and recurrent plaques in limbs with pustules in the right cheek, chest, abdomen and hips. Wells' syndrome was diagnosed and the following findings were documented: flame figures in the histological sections, negative immunofluorescence for immune complexes and complement deposits, peripheral blood eosinophilia, and Helicobacter pylori infection confirmed by endoscopy and gastric biopsy. Possible physiopathological mechanisms of a new association with H. pylori are discussed. It may be a coincidence or a possible etiology that should be further investigated. [ABSTRACT FROM AUTHOR]