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A novel lipase enzyme panel exhibiting superior activity and selectivity over lipase B from Candida antarctica for the kinetic resolution of secondary alcohols
- Source :
-
Tetrahedron: Asymmetry . Apr2012, Vol. 23 Issue 8, p583-586. 4p. - Publication Year :
- 2012
-
Abstract
- Abstract: A novel, commercially available lipase enzyme panel performing kinetic bioresolutions of a number of secondary alcohols is reported. The secondary alcohols that have been chosen are known from the literature to be particularly challenging substrates to resolve. Following initial screening, four co-solvents were investigated for each lead enzyme in an effort to assess their tolerance to common organic solvents. The superiority of these novel enzymes over lipase B from Candida antarctica (CALB) has been demonstrated. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 09574166
- Volume :
- 23
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Tetrahedron: Asymmetry
- Publication Type :
- Academic Journal
- Accession number :
- 76308523
- Full Text :
- https://doi.org/10.1016/j.tetasy.2012.03.013