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Effect of an exon 1 mutation in the myostatin gene on the growth traits of the Bian chicken.
- Source :
-
Animal Genetics . Aug2012, Vol. 43 Issue 4, p458-459. 2p. 1 Chart. - Publication Year :
- 2012
-
Abstract
- Myostatin ( MSTN), or growth and differentiation factor 8 ( GDF8), is a member of the transforming growth factor (TGF)-β superfamily. This family functions as a negative regulator of skeletal muscle development and growth in mammals. Single-nucleotide polymorphisms in exon 1 of the Bian chicken myostatin gene were detected by polymerase chain reaction-restriction fragment length polymorphism. A mutation (c.234G>A) in exon 1 was found. Female Bian chickens of genotypes AA and GA had significantly higher body weights than those of genotype GG ( P < 0.05 or P < 0.01) from 6 to 18 weeks of age. These results suggested that the mutation c.234G>A in exon 1 could be used as a genetic marker for Bian chicken growth traits. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 02689146
- Volume :
- 43
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Animal Genetics
- Publication Type :
- Academic Journal
- Accession number :
- 77510008
- Full Text :
- https://doi.org/10.1111/j.1365-2052.2011.02274.x