Actinobacillus pleuropneumoniae: pathobiology and pathogenesis of infection

Authors :: Bossé, Janine T.
Janson, Håkan
Sheehan, Brian J.
Beddek, Amanda J.
Rycroft, Andrew N.
Simon Kroll, J.
Langford, Paul R.
Source :: Microbes & Infection. Feb2002, Vol. 4 Issue 2, p225. 11p.
Publication Year :: 2002
Abstract: Actinobacillus pleuropneumoniae causes porcine pleuropneumonia, a highly contagious disease for which there is no effective vaccine. This review considers how adhesins, iron-acquisition factors, capsule and lipopolysaccharide, RTX cytotoxins and other potential future vaccine components contribute to colonisation, to avoidance of host clearance mechanisms and to damage of host tissues. [Copyright &y& Elsevier]