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An efficient method for synthesis of α-keto acid esters from terminal alkynes

Authors :
Li, Lian-Sheng
Wu, Yu-Lin
Source :
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Mar2002, Vol. 43 Issue 13, p2427. 4p.
Publication Year :
2002

Abstract

α-Keto acid esters can be easily prepared in high yields in two steps from terminal alkynes via bromination and oxidation. This strategy provides a versatile access to the synthesis of biologically important natural products with an α-keto acid moiety. [Copyright &y& Elsevier]

Subjects

Subjects :
*ESTERS
*KETONIC acids
*BROMINATION

Details

Language :
English
ISSN :
00404039
Volume :
43
Issue :
13
Database :
Academic Search Index
Journal :
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :
Academic Journal
Accession number :
7764018
Full Text :
https://doi.org/10.1016/S0040-4039(02)00290-3