Maternal and infant antiretroviral regimens to prevent postnatal HIV-1 transmission: 48-week follow-up of the BAN randomised controlled trial.

Authors :: Jamieson, Denise J.
Chasela, Charles S.
Hudgens, Michael G.
King, Caroline C.
Kourtis, Athena Ρ.
Kayira, Dumfaani
Hosseinipour, Mina C.
Kamwendo, Deborah D.
Ellington, Sascha R.
Wiener, Jeffrey Β.
Fiscus, Susan A.
Tegha, Gerald
Mofolo, Innocent A.
Sichali, Dorothy S.
Adair, Linda S.
Knight, Rodney J.
Martinson, Francis
Kacheche, Zebrone
Soto, Alice
Hoffman, Irving
Source :: Lancet. 6/30/2012, Vol. 379 Issue 9835, p2449-2458. 10p.
Publication Year :: 2012
Abstract: The article presents a study focusing on maternal and infant antiretroviral regimens to prevent postnatal HIV-1 transmission. It shows that in resource limited settings where no suitable alternative to breastfeeding is available, antiretroviral prophylaxis given to mothers or infants might decrease HIV transmission. It also showed that weaning at 6 months could increase the morbidity of infant. INSET: Panel: Research in context.

Subjects :: *HIV infection transmission
*ANTIRETROVIRAL agents
*BREASTFEEDING
*DISEASES
*INFANTS

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