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Successful treatment of a woman with relapsing neuromyelitis optica by interferon beta.
- Source :
-
Neurological Sciences . Aug2012, Vol. 33 Issue 4, p911-913. 3p. - Publication Year :
- 2012
-
Abstract
- Neuromyelitis optica (NMO) is an antibody-mediated disease with the target antigen being the water channel aquaporin-4 (AQP4). More than 90% of NMO patients have relapse. Optimal treatments to prevent recurrence have not been established. Previous reports suggest that interferon beta (IFNB) has not been effective in NMO. However, we present a case of NMO with positive anti-myelin oligodendrocyte glycoprotein (MOG) IgG and anti-AQP4 IgG treated with IFNB-1a successfully. The effect of IFNB on NMO and the role of anti-MOG antibodies in NMO deserve further study. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15901874
- Volume :
- 33
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Neurological Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 77735389
- Full Text :
- https://doi.org/10.1007/s10072-011-0849-0