An allosteric crown ether-induced activity control for the cleavage of a phosphodiester bond

Authors :: Tozawa, Tomokazu
Tokita, Sumio
Kubo, Yuji
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. May2002, Vol. 43 Issue 19, p3455. 3p.
Publication Year :: 2002
Abstract: Bis (thiourea) receptor 1 based on a highly flexible dibenzo-diaza-30-crown-10 scaffold represented a K+-organized microenvironment to markedly accelerate the cleavage of the phoshodiester linkage of the RNA model substrate (2-hydroxypropyl-p-nitrophenyl phosphate). [Copyright &y& Elsevier]

Language :: English
ISSN :: 00404039
Volume :: 43
Issue :: 19
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 7791718
Full Text :: https://doi.org/10.1016/S0040-4039(02)00601-9

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