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A novel contrast agent with rare earth-doped up-conversion luminescence and Gd-DTPA magnetic resonance properties
- Source :
-
Journal of Solid State Chemistry . Aug2012, Vol. 192, p75-80. 6p. - Publication Year :
- 2012
-
Abstract
- Abstract: The magnetic-luminescent multifunctional nanoparticles based on Gd-DTPA and NaYF4:Yb, Er were successfully synthesized by the conjugation of activated DTPA and silica-coated/surface-aminolated NaYF4:Yb, Er nanoparticles through EDC/NHS coupling chemistry. The as-prepared products were characterized by powder X-ray diffraction, transmission electron microscopy, dynamic light scattering, energy dispersive X-ray analysis, and fourier transform infrared spectrometry. The room-temperature upconversion luminescent spectra and T 1-weighted maps of the obtained nanoparticles were carried out by 980nm NIR light excitation and a 3T MR imaging scanner, respectively. The results indicated that the as-synthesized multifunctional nanoparticles with small size, highly solubility in water, and both high MR relaxivities and upconversion luminescence may have potential usage for MR imaging in future. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00224596
- Volume :
- 192
- Database :
- Academic Search Index
- Journal :
- Journal of Solid State Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 78031569
- Full Text :
- https://doi.org/10.1016/j.jssc.2012.03.016