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Eryngiolide A, a Cytotoxic Macrocyclic Diterpenoid with an Unusual Cyclododecane Core Skeleton Produced by the Edible Mushroom Pleurotus eryngii.
- Source :
-
Organic Letters . Jul2012, Vol. 14 Issue 14, p3672-3675. 4p. - Publication Year :
- 2012
-
Abstract
- Eryngiolide A (1), the first member of C20 diterpenoids with the skeleton deriving from a cyclododecane core fused with two γ-lactone units, was isolated from the solid culture of the edible mushroom Pleurotus eryngii. The structure of 1was elucidated by extensive analysis of NMR spectra. Compound 1exhibited moderate cytotoxicity against two human cancer lines in vitro. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15237060
- Volume :
- 14
- Issue :
- 14
- Database :
- Academic Search Index
- Journal :
- Organic Letters
- Publication Type :
- Academic Journal
- Accession number :
- 78034026
- Full Text :
- https://doi.org/10.1021/ol301519m