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A new auronol from Cudrania cochinchinensis.
- Source :
-
Journal of Asian Natural Products Research . Jul2012, Vol. 14 Issue 7, p704-707. 4p. 1 Diagram. - Publication Year :
- 2012
-
Abstract
- A new auronol, cudrauronol (1), was isolated from the roots of Cudrania cochinchinensis along with 10 known compounds, 1,3,5-trihydroxy-4-prenylxanthone (2), 1,3,7-trihydroxy-4-prenylxanthone (3), 3,4′,5,7-tetrahydroxydihydroflavonol (4), kaempferol (5), 3,6-dihydroxy-1,5-dimethoxyxanthone (6), 2′,4′,5,7-tetrahydroxyflavanolol (7), 3,7-dihydroxy-1-methoxyxanthone (8), 1,3,5-trihydroxyxanthone (9), cudraflavone B (10), and 2′-oxyresveratrol (11). Compounds 1–8 were evaluated for anti-inflammatory activity on lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages. Compounds 2–5 were more active than aminoguanidine, with IC50 values of 8.8, 23.2, 27.1, and 11.9 μM, respectively. [ABSTRACT FROM PUBLISHER]
Details
- Language :
- English
- ISSN :
- 10286020
- Volume :
- 14
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Journal of Asian Natural Products Research
- Publication Type :
- Academic Journal
- Accession number :
- 78141056
- Full Text :
- https://doi.org/10.1080/10286020.2012.682305