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Association between interaction and ratio of ω-3 and ω-6 polyunsaturated fatty acid and the metabolic syndrome in adults
- Source :
-
Nutrition . Sep2012, Vol. 28 Issue 9, p856-863. 8p. - Publication Year :
- 2012
-
Abstract
- Abstract: Objective: To investigate the association of the intakes of ω-3 (including α-linolenic acid [ALA], eicosapentaenoic acid [EPA] plus docosahexaenoic acid [DHA]) and ω-6 polyunsaturated fatty acids (PUFAs), the interaction, and the ratio of these PUFAs with the metabolic syndrome (MetS) in adults. Methods: This cross-sectional study was conducted in a random sample of participants (n = 2451, 19–84 y old) in the Tehran Lipid Glucose Study. Dietary intake was assessed using a validated semiquantitative food-frequency questionnaire. Anthropometric characteristics, blood pressure, and fasting plasma concentrations of glucose and lipids were measured. The MetS was defined according to the Adult Treatment Panel III guidelines. Results: Among the PUFAs, the ALA and ω-6 PUFA intakes were inversely associated with the MetS. Subjects in the highest quartile of ALA and ω-6 fatty acid intakes had a 38% (odds ratio 0.62, 95% confidence interval 0.41–0.95) and a 0.47% (odds ratio 0.53, 95% confidence interval 0.31–0.89) lower prevalence of MetS, respectively, compared with those in the lowest quartile. The dietary ratio of ω-6 to ω-3 fatty acids was not associated with the MetS. When the interaction between ALA and ω-6 fatty acid was assessed, the ALA intake was associated with a lower prevalence of the MetS, without modification by the ω-6 PUFA intake. Subjects with at least the median ALA intake (1084 mg/d) had a lower prevalence of the MetS, irrespective of an ω-6 PUFA intake lower or higher than the median compared with subjects with intakes below the median for both. Conclusion: The ALA intake was inversely associated with the MetS, irrespective of the background intake of ω-6 PUFAs, in adults. [Copyright &y& Elsevier]
- Subjects :
- *OBESITY
*HYPERLIPIDEMIA
*METABOLIC syndrome diagnosis
*BIOCHEMISTRY
*BODY weight
*CARDIOVASCULAR diseases risk factors
*CHI-squared test
*DEMOGRAPHY
*HIGH density lipoproteins
*INGESTION
*EVALUATION of medical care
*NUTRITION
*OMEGA-3 fatty acids
*OMEGA-6 fatty acids
*DATA analysis
*BODY mass index
*ACQUISITION of data
*CROSS-sectional method
*GLUCOSE intolerance
*PHYSICAL activity
*DATA analysis software
*DESCRIPTIVE statistics
*DIAGNOSIS
Subjects
Details
- Language :
- English
- ISSN :
- 08999007
- Volume :
- 28
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 78279910
- Full Text :
- https://doi.org/10.1016/j.nut.2011.11.031