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Novel Stereocontrolled Addition of Allylmetal Reagents to α-Imino Esters: Efficient Synthesis of Chiral Tetrahydroquinoline Derivatives.

Authors :
Di Fabio, Romano
Alvaro, Giuseppe
Bertani, Barbara
Donati, Daniele
Giacobbe, Simone
Marchioro, Carla
Palma, Carlotta
Lynn, Sean M.
Source :
Journal of Organic Chemistry. 10/18/2002, Vol. 67 Issue 21, p7319. 10p. 6 Diagrams, 3 Charts.
Publication Year :
2002

Abstract

Examines the stereocontrolled addition of allylmetal reagents to α-imino esters. Synthesis of chiral tetrahydroquinoline derivatives; Preparation of multigram scale for glycine binding site; Allylation reaction of efficient stereodifferentiation process; Illustration on Heck-type cyclization reaction for trisubstituted double bond derivatives.

Subjects

Subjects :
*CHEMICAL reagents
*CHIRALITY

Details

Language :
English
ISSN :
00223263
Volume :
67
Issue :
21
Database :
Academic Search Index
Journal :
Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
7902146
Full Text :
https://doi.org/10.1021/jo020327d