Herpes simplex virus vaccines: what’s new?

Herpes simplex viruses (HSV) can cause a variety of infections, including genital herpes. Despite effective antiviral therapy HSV infections remain a public health problem. Vaccines offer the possibility for controlling the spread and limiting HSV disease, two strategies for herpes vaccination: prophylactic immunization or therapeutic immunization. The article discusses the results of differents studies, in particular, concerning recombinant vaccines, DISC vaccines and DNA vaccines. [Copyright &y& Elsevier]