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Extensive diversity of Trypanosoma cruzi discrete typing units circulating in Triatoma dimidiata from central Veracruz, Mexico
- Source :
-
Infection, Genetics & Evolution . Oct2012, Vol. 12 Issue 7, p1341-1343. 3p. - Publication Year :
- 2012
-
Abstract
- Abstract: Chagas disease (or American trypanosomiasis) is a parasitic disease of major public health importance, caused by Trypanosoma cruzi, which presents extensive genetic diversity. The parasite has been classified into six lineages or discrete typing units (TcI to TcVI) and we performed here the molecular characterization of the strains present in Triatoma dimidiata, the main vector in central Veracruz, Mexico. Unexpectedly, TcI only represented 9/33 strains identified (27%), and we reported for the first time the presence of TcII, TcIII, TcIV and TcV strains in Mexico, at a relatively high frequency (13–27% each). Our observations indicate a much greater diversity of T. cruzi DTUs than previously estimated in at least part of Mexico. These results have important implications for the understanding of the phylogeography of T. cruzi DTUs and the epidemiology of Chagas disease in North America. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 15671348
- Volume :
- 12
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Infection, Genetics & Evolution
- Publication Type :
- Academic Journal
- Accession number :
- 79338047
- Full Text :
- https://doi.org/10.1016/j.meegid.2012.04.024