Back to Search
Start Over
Four-Dimensional Measurement of the Displacement of Internal Fiducial and Skin Markers During 320-Multislice Computed Tomography Scanning of Breast Cancer
- Source :
-
International Journal of Radiation Oncology, Biology, Physics . Oct2012, Vol. 84 Issue 2, p331-335. 5p. - Publication Year :
- 2012
-
Abstract
- Purpose: To study the three-dimensional movement of internal tumor bed fiducial and breast skin markers, using 320-multislice computed tomography (CT); and to analyze intrafractional errors for breast cancer patients undergoing breast irradiation. Methods and Materials: This study examined 280 markers on the skin of the breast (200 markers) and on the primary tumor bed (80 markers) of 20 patients treated by external-beam photon radiotherapy. Motion assessment was analyzed in 41 respiratory phases during 20 s of cine CT in the radiotherapy position. To assess intrafractional errors resulting from respiratory motion, four-dimensional CT scans were acquired for 20 patients. Results: Motion in the anterior–posterior (A/P) and superior–inferior (S/I) directions showed a strong correlation (|r| > 0.7) with the respiratory curve for most markers (79% and 70%, respectively). The average marker displacements between maximum and minimum value during 20 s for the 200 breast skin metal markers were 1.1 ± 0.3 mm, 2.1 ± 0.6 mm, and 1.6 ± 0.4 mm in the left–right, A/P, and S/I directions, respectively. For the 80 tumor bed clips, displacements were 0.9 ± 0.2 mm in left–right, 1.7 ± 0.5 mm in A/P, and 1.1 ± 0.3 mm in S/I. There was no significant difference in the motion between breast quadrant regions or between the primary site and the other regions. Conclusions: Motion in primary breast tumors was evaluated with 320-multislice CT. Very little change was detected during individual radiation treatment fractions. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 03603016
- Volume :
- 84
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- International Journal of Radiation Oncology, Biology, Physics
- Publication Type :
- Academic Journal
- Accession number :
- 79559974
- Full Text :
- https://doi.org/10.1016/j.ijrobp.2011.12.030