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Central nervous system aquaporin-4 autoimmunity presenting with an isolated cerebral abnormality.
- Source :
-
Multiple Sclerosis Journal . Sep2012, Vol. 18 Issue 9, p1340-1343. 4p. 1 Color Photograph. - Publication Year :
- 2012
-
Abstract
- Advances in the understanding of central nervous system aquarporin-4 autoimmunity have promoted the recognition of diverse clinical presentations beyond the traditional view of neuromyelitis optica. We describe a patient who developed hemiparesis caused by an extensive cerebral lesion as an initial manifestation of central nervous system aquarporin-4 autoimmunity. Although the patient had no history of optic neuritis or myelitis, not only was serum anti-aquarporin-4 antibody positive, but an imaging, treatment response and histopathological features also revealed characteristic findings suggestive of central nervous system aquarporin-4 autoimmunity. The present case highlights the importance of a comprehensive evaluation for anti-aquarporin-4 antibody even in patients presenting with isolated cerebral lesions. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13524585
- Volume :
- 18
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Multiple Sclerosis Journal
- Publication Type :
- Academic Journal
- Accession number :
- 79772912
- Full Text :
- https://doi.org/10.1177/1352458512441271