Nanorods Formed from aNew Class of Peptidomimetics.

Although peptide amphiphiles have been explored as nanomaterialsfor different applications, nanostructures formed by hierarchicalmolecular assembly of sequence-specific peptidomimetics are much lessdeveloped. Such protein-like nanomaterials could enhance the currentapplication of peptide-based amphiphiles by enriching the diversityof nanostructures, increasing in vivostability forbiomedical applications, and facilitating the understanding of biomacromolecularself-assembly. Herein we present a biomimetic γ-AApeptide amphiphilewhich forms nanorods. Our results demonstrate the capability of γ-AApeptideamphiphiles as a potential scaffold for the preparation of biomimeticand bioinspired nanostructures. The programmability and biocompatibilityof γ-AApeptides could lead to novel nanomaterials for a widevariety of applications. [ABSTRACT FROM AUTHOR]