Back to Search
Start Over
A rhodamine-deoxylactam based sensor for chromo-fluorogenic detection of nerve agent simulant
- Source :
-
Bioorganic & Medicinal Chemistry Letters . Oct2012, Vol. 22 Issue 20, p6358-6361. 4p. - Publication Year :
- 2012
-
Abstract
- Abstract: N-(rhodamine B)-deoxylactam-5-amino-1-pentanol (dRB-APOH) was designed and prepared as the chromo-fluorogenic sensor for detection of a nerve agent simulant via analyte triggered tandem phosphorylation and opening of the intramolecular deoxylactam. The successful detection of diethyl chlorophosphate suggests the utility of rhodamine-deoxylactams as the chromo-fluorogenic signal reporting platform for design of sensors targeting reactive chemical species via various chemistries. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 0960894X
- Volume :
- 22
- Issue :
- 20
- Database :
- Academic Search Index
- Journal :
- Bioorganic & Medicinal Chemistry Letters
- Publication Type :
- Academic Journal
- Accession number :
- 82062688
- Full Text :
- https://doi.org/10.1016/j.bmcl.2012.08.077