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The trifluoromethyl transformation synthesis, crystal structure and insecticidal activities of novel 2-pyrrolecarboxamide and 2-pyrrolecarboxlate
- Source :
-
Bioorganic & Medicinal Chemistry Letters . Nov2012, Vol. 22 Issue 22, p6858-6861. 4p. - Publication Year :
- 2012
-
Abstract
- Abstract: Two series of 2-phenylpyrroles: 3-bromo-5-(4-chlorophenyl)-4-cyanopyrrole-2-carboxamide (5a–5d) and 3-bromo-5-(4-chlorophenyl)-4-cyanopyrrole-2-carboxylate (6a–6c) were synthesized by a novel trifluoromethyl transformation. The result of insecticidal bioassays indicated that 6a–6c had moderate larvicidal activity against oriental armyworm and 6b also had good acaricidal activity, so 3-bromo-5-(4-chlorophenyl)-4-cyanopyrrole-2-carboxylate derivatives were expected to become lead compounds for new pesticides. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 0960894X
- Volume :
- 22
- Issue :
- 22
- Database :
- Academic Search Index
- Journal :
- Bioorganic & Medicinal Chemistry Letters
- Publication Type :
- Academic Journal
- Accession number :
- 82597794
- Full Text :
- https://doi.org/10.1016/j.bmcl.2012.09.036