Synthesis of dialkyl and diaryl benzylphosphonates through a ZnI2-mediated reaction

Authors :: Richardson, Rebekah M.
Barney, Rocky J.
Wiemer, David F.
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Dec2012, Vol. 53 Issue 49, p6682-6684. 3p.
Publication Year :: 2012
Abstract: Abstract: Several trialkyl and two triaryl phosphites have been tested for their reactivity in the zinc iodide mediated conversion of benzyl alcohol to the corresponding phosphonates. Most react smoothly to afford the desired phosphonate diesters, including hindered and nonracemic phosphites. The implications of this reactivity on the reactions involved in the transformation are discussed. [Copyright &y& Elsevier]

Subjects :: *PHOSPHONATES
*ORGANIC synthesis
*CHEMICAL reactions
*REACTIVITY (Chemistry)
*IODIDES
*BENZYL alcohol
*PHOSPHITES

Language :: English
ISSN :: 00404039
Volume :: 53
Issue :: 49
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 83214369
Full Text :: https://doi.org/10.1016/j.tetlet.2012.09.114

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