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An RNA Mapping DataBase for curating RNA structure mapping experiments.
- Source :
-
Bioinformatics . Nov2012, Vol. 28 Issue 22, p3006-3008. 3p. - Publication Year :
- 2012
-
Abstract
- Summary: We have established an RNA mapping database (RMDB) to enable structural, thermodynamic and kinetic comparisons across single-nucleotide-resolution RNA structure mapping experiments. The volume of structure mapping data has greatly increased since the development of high-throughput sequencing techniques, accelerated software pipelines and large-scale mutagenesis. For scientists wishing to infer relationships between RNA sequence/structure and these mapping data, there is a need for a database that is curated, tagged with error estimates and interfaced with tools for sharing, visualization, search and meta-analysis. Through its on-line front-end, the RMDB allows users to explore single-nucleotide-resolution mapping data in heat-map, bar-graph and colored secondary structure graphics; to leverage these data to generate secondary structure hypotheses; and to download the data in standardized and computer-friendly files, including the RDAT and community-consensus SNRNASM formats. At the time of writing, the database houses 53 entries, describing more than 2848 experiments of 1098 RNA constructs in several solution conditions and is growing rapidly.Availability: Freely available on the web at http://rmdb.stanford.eduContact: rhiju@stanford.eduSupplementary information: Supplementary data are available at Bioinformatics Online. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DATABASES
*DATA mapping
*NUCLEOTIDE sequence
*META-analysis
*BIOINFORMATICS
Subjects
Details
- Language :
- English
- ISSN :
- 13674803
- Volume :
- 28
- Issue :
- 22
- Database :
- Academic Search Index
- Journal :
- Bioinformatics
- Publication Type :
- Academic Journal
- Accession number :
- 83483864
- Full Text :
- https://doi.org/10.1093/bioinformatics/bts554