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Genetic polymorphisms and childhood acute lymphoblastic leukemia: GWAS of the ESCALE study (SFCE).

Authors :
Orsi, L
Rudant, J
Bonaventure, A
Goujon-Bellec, S
Corda, E
Evans, T-J
Petit, A
Bertrand, Y
Nelken, B
Robert, A
Michel, G
Sirvent, N
Chastagner, P
Ducassou, S
Rialland, X
Hémon, D
Milne, E
Scott, R J
Baruchel, A
Clavel, J
Source :
Leukemia (08876924). Dec2012, Vol. 26 Issue 12, p2561-2564. 4p. 2 Charts.
Publication Year :
2012

Abstract

The article presents the results of the genome-wide association studies (GWAS) conducted on the cases of acute lymphoblastic leukaemia (ALL) from the nationwide registry-based study and generic controls of Etude Sur les Cancers et les Leucémies de l'Enfant (ESCALE). The case-control study considered single-nucleotide polymorphisms (SNPs) associated with AL in the GWAS. The positive relationships between common B-cell ALL subtypes and ARID5B SNPs were also observed.

Details

Language :
English
ISSN :
08876924
Volume :
26
Issue :
12
Database :
Academic Search Index
Journal :
Leukemia (08876924)
Publication Type :
Academic Journal
Accession number :
84140202
Full Text :
https://doi.org/10.1038/leu.2012.148