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The CD70-CD27 Axis, a New Brake in the T Helper 17 Cell Response

Authors :
Wang, Xiaohu
Dong, Chen
Source :
Immunity (10747613). Jan2013, Vol. 38 Issue 1, p1-3. 3p.
Publication Year :
2013

Abstract

The CD70-CD27 interaction is known to positively regulate T cell expansion and effector function by providing costimulatory signals. In this issue of Immunity, Coquet et al. (2013) show an unexpected T-helper-17-cell-specific negative regulation mediated by CD70-CD27 interaction. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*CD antigens
*T helper cells
*CELLULAR signal transduction
*PROTEIN-protein interactions
*CELLULAR control mechanisms
*IMMUNITY

Details

Language :
English
ISSN :
10747613
Volume :
38
Issue :
1
Database :
Academic Search Index
Journal :
Immunity (10747613)
Publication Type :
Academic Journal
Accession number :
85155112
Full Text :
https://doi.org/10.1016/j.immuni.2013.01.005
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