The resolution of aglinin A epimers and their NMR assignments.

Authors :: Feng, Tian-Xiang
Qu, Shi-Jin
Tan, Jun-Jie
Jiang, Kun
Tan, Chang-Heng
Lin, Shuang-Jun
Source :: Journal of Asian Natural Products Research. Jan2013, Vol. 15 Issue 1, p89-93. 5p. 3 Diagrams, 1 Chart.
Publication Year :: 2013
Abstract: Aglinin A (1) is a mixture of C24-epimeric 20S,24-epoxy-24,25-dihydroxy-3,4-secodammar-4(28)-en-3-oic acid and present in plants of the family Meliaceae. The two epimers of 1 were resolved through an acetonide reaction, and the absolute configurations of two derivatives were deduced by the analysis of their 13C NMR differences induced by γ-gauche or steric effect. Based on it, the 13C NMR assignment of 24R-1 and 24S-1 was also established. [ABSTRACT FROM AUTHOR]