Post-chemoreduction cryptic optic nerve relapse in a patient with bilateral retinoblastoma.

The article presents a case study of a 20-month-old patient diagnosed with sporadic bilateral retinoblastoma and Group D in the right eye (RE) with complete retinal detachment. It provides several questions such as what diagnostic tests to perform and how to interpret histopathology of the globe and optic nerve. It mentions that the growth of isolated optic nerve retinoblastoma without histopathologic contiguity shows the existence of postlaminar optic nerve tumour activity.