Deposition Strategies for Osmium/Enzyme Films on Gold Electrode Based Sensing Arrays.

Multi-analyte real-time interrogation of cellular activity allows for the potential discovery of novel insights into disease. In this report, the addition of electrochemical biosensors to a previously developed platform utilizing Au microfabricated electrodes was explored. Glucose oxidase was immobilized at the electrode surface with an osmium redox polymer, using hand-casting and electrodeposition techniques, allowing for the first comparison of deposition techniques at a Au microfabricated array. This preliminary work is the first step toward the goal of creating a multi-analyte array for cellular analysis. [ABSTRACT FROM AUTHOR]