Immune downregulation leads to upregulation of an antiviral response: a lesson from the hepatitis B virus

Induction of tolerance towards antigens that drive susceptibility or pathology may be considered a new mode of treatment for several infections. Hepatitis B virus is a non-cytopathic virus, and oral immune regulation was shown to be effective in modulation of the immune-mediated liver injury. [Copyright &y& Elsevier]