Analysis of Deoxynivalenol, Zearalenone, T-2, and HT-2 Toxins in Animal Feed by LC/MS/MS--A Critical Comparison of Immunoaffinity Column Cleanup with No Cleanup.

The article discusses the results of a study that compares the liquid chromatography-tandem mass spectrometry (LC/MS/MS) method and a method using acetonitrile extraction and subsequent immunoaffinity column (IAC) cleanup. The study shows poor performance of the method without cleanup than the method with IAC cleanup in terms of identification based on ion ratios. Also, repeatability was poor with no cleanup.