EVALUATION OF ANTIOXIDANT ACTIVITY, CYTOTOXIC STUDIES AND GC-MS PROFILING OF MATTHIOLA INCANA (STOCK FLOWER).

Antioxidant activity of Matthiola incana flowers extracted with different solvents like petroleum ether, chloroform, ethyl acetate, absolute methanol, methanol water (9.5:0.5) methanol water (9:1) extracts of stock flower (Matthiola incana) were analyzed. The total phenolics content (TPC) were found in the range of 0.327-1.872 mg GAE/g and total flavonoids content (TFC) were found in the range 2.06-6.067 CE mg/g. Other parameters studied were reducing power, DPPH radical scavenging and inhibition of linoleic acid per oxidation. The antioxidant activity of the Matthiola incana was also evaluated by measuring the conjugated dienes (CD), conjugated triene (CT), p-anisidine value (PAV), free fatty acid (FFA) and peroxide values (PV) by using canola oil as an oxidative substrate. The n-hexhane extract was also analyzed by GC-MS. The methanolic extracts of Matthiola incana flowers showed maximum antioxidant activity. The cytotoxicity studies was also studied by haemolytic activity of the plant extracts against the human erythrocytes (RBC's) was found to be in the range of 0.91-4.47 %. [ABSTRACT FROM AUTHOR]