The Effect of Glucosamine Sulfate on the Proliferative Potential and Glycosaminoglycan Synthesis of Nucleus Pulposus Intervertebral Disc Cells.

A study on the effect of glucosamine sulfate on nucleus pulposus intervertebral disc cells. Glucosamine sulfate's role in proliferation of nucleus pulposus cells under iso- and hyperosmotic conditions is examined. The study found that glucosamine sulfate cannot reverse the high osmolality-mediated delay of proliferation in nucleus pulposus cells. A possible clinical roles for treating disc degenerative disorders are exhibited.