Back to Search
Start Over
Higher heart rate increases risk of diabetes among men: The Australian Diabetes Obesity and Lifestyle (AusDiab) Study.
- Source :
-
Diabetic Medicine . Apr2013, Vol. 30 Issue 4, p421-427. 7p. 2 Charts, 1 Graph. - Publication Year :
- 2013
-
Abstract
- Aims A very limited number of prospective studies have reported conflicting data on the relation between heart rate and diabetes risk. Our aim therefore was to determine in a large, national, population-based cohort if heart rate predicts the development of diabetes. Methods The Australian Diabetes Obesity and Lifestyle study followed up 6537 people over 5 years. Baseline measurements included questionnaires, anthropometrics and blood and urine collection. Heart rate was recorded in beats per min (Dinamap). An oral glucose tolerance test was performed at baseline and follow-up, and diabetes was defined using World Health Organization criteria. Results A total of 5817 participants were eligible for analysis, 221 of whom developed diabetes. Compared with participants with a heart rate < 60 b min-1, those with a heart rate ≥ 80 b min-1 were more likely to develop diabetes (odds ratio 1.89, 95% CI 1.07-3.35) over 5 years, independent of traditional risk factors. This relationship was highly significant, particularly in non-obese men (odds ratio 5.61, 95% CI 1.75-17.98), but not in their obese counterparts or in women. Conclusions Resting heart rate is associated with an increased risk of diabetes over a 5-year period, particularly among non-obese men. This suggests that sympathetic overactivity may be a contributing factor to the development of diabetes, and that resting heart rate may be useful in predicting risk of Type 2 diabetes in non-obese men. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DIABETES risk factors
*SMOKING
*OBESITY complications
*BLOOD pressure
*BLOOD pressure measurement
*CONFIDENCE intervals
*DIABETES
*PEOPLE with diabetes
*EDUCATION
*HEART rate monitoring
*HOMEOSTASIS
*LONGITUDINAL method
*MEDICAL societies
*SERIAL publications
*DATA analysis
*BODY mass index
*LIFESTYLES
*ACQUISITION of data
*DATA analysis software
Subjects
Details
- Language :
- English
- ISSN :
- 07423071
- Volume :
- 30
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Diabetic Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 86146998
- Full Text :
- https://doi.org/10.1111/dme.12045