Studying 18 MDa Virus Assemblies with Native Mass Spectrometry.

Authors :: Snijder, Joost
Rose, Rebecca J.
Veesler, David
Johnson, John E.
Heck, Albert J. R.
Source :: Angewandte Chemie International Edition. Apr2013, Vol. 52 Issue 14, p4020-4023. 4p.
Publication Year :: 2013
Abstract: Setting records: Native mass spectometry was used to study the assembly of the 18 MDa capsid of bacteriophage HK97. The previous record for the analysis of capsids by this method was around 10 MDa. The results indicate that the efficiency of desolvation is the main priority in improving native MS instrumentation. [ABSTRACT FROM AUTHOR]