PML NBs associate with the HMre11 complex and p53 at sites of irradiation induced DNA damage.

Authors :: Carbone, Roberta
Pearson, Mark
Minucci, Saverio
Pelicci, Pier Guiseppe
Source :: Oncogene. 3/7/2002, Vol. 21 Issue 11, p1633. 8p. 6 Diagrams.
Publication Year :: 2002
Abstract: Presents a study that examined the modification of promyelocytic leukemia protein nuclear bodies (PML NB) and the recognition of sites of DNA breaks in human fibroblasts after ionizing radiation. Functions of PML NB; Background on PML; Characteristics of acute promyelocytic leukemia; Components of PML NB; Types of damage response pathways.

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