Non-covalent Sugar Modification and Self-assembly of Fluorous Gold Nanoparticles Driven by Fluorous Interaction.

Fluorous gold nanoparticle ( Fluo-NP), i.e. gold nanoparticle covered by fluorous ponytail (C8F17-) was prepared and found to self-assemble into supra-structures covered by carbohydrates (named supraF-NP), due to the strong fluorous interaction. More importantly, the re-dispersed supraF-NP (diameter around 200 nm) in water provided an alternative strategy to detect carbohydrate-protein interaction in solution by naked eye. [ABSTRACT FROM AUTHOR]